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7. Takeda, S., Usami, N., Yamamoto, I., & Watanabe, K. (2009). Cannabidiol-2′, 6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. 8. Lascelles, B. D. X., King, S., Roe, S., Marcellin-Little, D. J., & Jones, S. (2009). Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from canines with naturally occurring coxofemoral joint osteoarthritis. 3. Aviram, J., Samuelly-Leichtag, G. (2017) Efficacy of Cannabis-Based Medicines for Pain Management: A scientific Review and Meta-Analysis of Randomized Controlled Trials. 1. Brand, E. J., & Zhao, Z. (2017). Cannabis in Chinese Medicine: Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids?. Its anti-inflammatory and neuroprotective properties enable the cannabinoid to relieve pain and improve regeneration capacities. The painkilling properties of cannabidiol have been most completely studied in animal fashions, as well as a handful of human clinical trials. Use A Chaser – In case you don’t care for the taste, strive chasing it together with your favorite beverage or dilute it with a glass of water to masque the cannabidiol taste.